Medical cannabis (i.e., marijuana) has been demonstrated in numerous studies to be a viable alternative to prescription painkillers. Marijuana’s intoxicating qualities, on the other hand, keep many people away. Cannabidiol (CBD), a non-intoxicating component present in cannabis, is used to treat a variety of ailments including pain alleviation. We noticed that some of the top CBD oils might aid with pain management treatment.
CBD oil, on the other hand, is not intended to be used as a pain treatment. However, it’s crucial to understand that CBD oil isn’t FDA-approved for pain relief. As a result, the items and claims made in this post are not regulated by the FDA. They are only meant to tell you whether your pet has potentially toxic mold or fungus.
There has been a lot of interest in CBD, even before the FDA’s review. You’ve undoubtedly heard about CBD on national news programs and read about it being recommended by high-profile social figures for a variety of pain relief.
How Does CBD Work?
Cannabis has been used to treat pain and inflammation for thousands of years. Cannabis has been prescribed in China as far back as 2737 BC, when Emperor Shen-Nung included it in the Chinese pharmacopeia together with other therapeutic medications. For the purpose of boosting recovery, leaves were used as a poultice to relieve pain and discomfort.
Despite its popularity, researchers have just begun to comprehend the mechanisms by which cannabis alleviates pain. The endocannabinoid system has been in the limelight of modern medicine since 1992, when scientists discovered it. CBD and other phytocannabinoids have been in the spotlight of modern medicine since 1992, when researchers discovered the endocannabinoid system.
The endocannabinoid system, one of the body’s most essential neurochemical systems, is made up of a number of components. It connects with the endocannabinoid system, a network of hormones and receptors that aids in numerous bodily processes. Cannabis plant chemicals are essentially identical to our natural hormones produced via the endocannabinoid system.
Cannabidiol (CBD) and other cannabinoids have the ability to affect a number of critical activities via their interactions with the endocannabinoid system, including:
- Immune function
- Sensory perception (including pain)
- Reproductive health
- Nerve function
How Can CBD Reduce Pain Transmission?
What does this signify? The meaning of this may be discovered in how pain is carried to the brain. When we harm ourselves, adjacent cells discharge chemicals that create a chain reaction of inflammation and sensation generation, resulting in pain transmission.
The sensation of suffering is then carried to the spinal cord via a network of nerves that runs the entire body. The pain signal is sent into the spine, where it is picked up by a checkpoint (opioid and vanilloid receptors) intended to limit the amount of data transmitted to the brain for processing. This acts as a passport control. Immigration officials decide whether you’re allowed in and what you can take with you.
The following are some of the most common causes of back pain: The discomfort must be stopped at a barrier in order to avoid causing more pain. In particular, these barriers can minimize the amount of pain signal that reaches the brain. If more pain signals are permitted to pass through, the brain perceives greater discomfort. Pain pills function by interacting with opioid receptors, which are key traffic entranceways for transporting pain information to the brain.
CBD works in a similar manner, however it binds to a different receptor called the vanilloid receptors. The nociceptive pain sensations induced by heat or irritation are controlled by these vanilloid receptors. CBD has been found to modulate this vanilloid receptor, reducing inflammatory causes of pain such as arthritis, muscular damage, and infection-induced pain.
Other non-THC cannabinoids have additional approaches to limit pain transmission as well:
- Cannabidiol (CBD) has anti-inflammatory effects that may help with a number of health problems.
- CBD, among other things, helps the body’s resistance to and recovery from harm by acting as an antioxidant.
- CBD helps with muscular spasms and tightness, resulting in less suffering.
There’s still a lot more study to be done in order to fully comprehend how CBD and other active cannabinoids can assist with pain. Hundreds of new research papers are published each year in an attempt to establish a solid understanding of how CBD works, what the drug’s advantages are, and where its limits exist.
What Do the Studies Say?
CBD’s therapeutic potential is being explored more frequently, with researchers particularly interested in how it might help with pain. In the European Journal of Pain, researchers investigated CBD’s effect on rats with arthritis-induced inflammation. For four days, scientists applied CBD gels to the rats’ arthritic joints at four different dosages (0.6, 3.1, 6.2, and 62.3mg) per day (n = 8).
The researchers discovered that CBD gel reduces joint swelling by a staggering 100 percent. Surprisingly, the 62.3mg dose was no more effective than the 6.2mg dose.
Meanwhile, researchers studied the anti-inflammatory capabilities of CBD in mice in a Frontiers in Immunology paper that came out last year. After ten days of treatment with CBD, inflammatory indicators decreased in mice. To mimic the symptoms of multiple sclerosis on a person’s body, they used a mouse model of encephalitis to induce neurologic impairment.
In scientific studies, cannabidiol was found to make pain seem less unpleasant, although it did not lower experimental pain intensity.
In 2021, researchers at Syracuse University repeated the CBD experiment from 2016. It’s significant because it was the first ever clinical pain study to evaluate CBD’s effect on people. According to the results, cannabidiol reduced experimental pain unpleasantness but not intensity.
According to a study published in November 2017, CBD was found to be more effective than a placebo in alleviating pain symptoms. This is undoubtedly a significant step toward acceptance of CBD as a pain-relieving option.
Using CBD Oil for Pain
The most common way to consume CBD oil is by putting a drop under your tongue and holding it for up to 60 seconds before swallowing. This technique ensures that some of the CBD goes into your circulation via your mouth.
However, applying CBD oil to a painful area may be more effective. Topical cannabidiol medications absorb more quickly than CBD oil. People who massage CBD on their skin frequently report improved results.
If you’re using CBD for the first time, only apply it to a little region of skin. You must exercise caution so that no undesirable effects occur. Increase the quantity you use until you reach the “minimum therapeutic dose,” which is a term used to describe a situation in which you employ the smallest amount feasible in order To get the intended result.
Benefits of CBD Oil – Anecdotal Evidence
CBD oil, however, is not yet recognized by the FDA as a pain remedy, but it improves the lives of millions of individuals throughout the world. Here are some of the feedback we’ve received about CBD’s influence on day-to-day discomfort:
Best CBD Oil for Pain: Side Effects
Hemp oil has some adverse side effects, despite the fact that it is as safe as CBD. When compared to the severe negative effects associated with prescription painkillers and other narcotic pain relievers, these minor problems appear to be nothing more than annoyances.
The most effective source for demonstrating CBD’s drawbacks is Epidiolex (a FDA-approved cannabidiol therapy for two uncommon types of epilepsy), according to clinical trials. Cannabidiol users may experience the following negative side effects, according to the research:
- Decreased appetite
- Transaminase elevations
- Fatigue, malaise, and asthenia
- Insomnia, sleep disorder, and poor-quality sleep
CBD has also been found to have negative interactions with a variety of other medicines, including over-the-counter and prescription medications. Furthermore, it has been claimed that CBD usage might harm your liver; however, this has yet to be researched. CBD is also a known accelerator for enzymes and drug metabolism. As a result, before using CBD in addition to other medicines for pain, it is important to discuss this with your doctor.
Let’s look at the top CBD oil brands and their product lines now that you know more about how CBD oil for pain works! Do you want to read or see a full explanation of our top CBD oil selections? Rather, here is a short summary of our video CBD oil countdown.